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Based on 14 reviews of intervention studies (seven high-quality), the researchers found that of 21 meta-analytic comparisons of nicotine EC versus other interventions, all reported point estimates favoring nicotine EC for smoking cessation, with relative risks or odds ratios ranging from 1.17 to 1.67 versus nicotine replacement therapy and 1.46 to 2.09 versus non-nicotine EC

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Study Methodology Researchers recruited 3,430 8-year-old children in northern Sweden and asked them to fill in questionnaires annually until they turned 19 and again when they reached the age of 28