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Early-life gut microbiota imbalances may predispose individuals to PTSD susceptibility after trauma exposure (Leclercq et al., 2016)

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The GCH1/BH4 pathway acts as an endogenous antioxidant pathway, GCH1 protects cells from ferroptosis primarily through the antioxidant action of BH4, and is completely independent of GPX4-mediated protection against ferroptosis [44]

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