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The Food and Drug Administration (FDA) has authorized two categories of epigenetic-modifying medications: DNA methylation inhibitors (including 5-azacitidine and Decitabine) and histone deacetylase inhibitors (such as Vorinostat, Belinostat, Romidepsin, and Panobinostat) [20, 21]

Although Chac2 has also been proposed to function as a GSH-degrading enzyme based on its approximately 50% sequence similarity to Chac1 , it shows about 20-fold lower catalytic efficiency than Chac1 on GSH degradation (20)

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Use a basic, gentle cleanser (like Foxtales Daily Duet) at all other times