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Tobacco use alone doesnt usually determine approval, but it does affect both pricing and eligibility when combined with certain health conditions

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So while acetylcholine normally provides the just the right amount of alertness when it b inds to its receptors, nicotine produces a much more intense response (increased alertness, pleasurable feelings) due to its higher concentrations at the acetylcholine receptors

5 : 18621867 Califano J, van der Riet P, Westra W, Nawroz H, Clayman G, Piantadosi S, Corio R, Lee D, Greenberg B, Koch W, Sidransky D

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