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[110] If successful through the stages of clinical development, the vaccine licensing process is followed by a Biologics License Application which must provide a scientific review team (from diverse disciplines, such as physicians, statisticians, microbiologists, chemists) and comprehensive documentation for the vaccine candidate having efficacy and safety throughout its development

15 ) and later replicated by multiple GWASs 10,11

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For research purposes, de-identified data are accessible upon application through the NHIS Big Data Platform ( Applicants are required to submit a research proposal (including study aims, cohort definition and a data specification), documentation of institutional review board approval, and other materials requested by NHIS