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Controlling for sex, age, working status at onset of disease, history of narcotic abuse, co-existing medical illness and the absence of contact history within five years in logistic regression, ever-smoking TB cases were significantly more likely to present with a cough and difficult or labored breathing, and less likely to present with only extrathoracic TB than never-smoking TB cases

The biomarkers analyzed including heavy metals, cancer-causing compounds known as polycyclic aromatic hydrocarbons and toxic gaseous chemicals called volatile organic compounds were measured at the Centers for Disease Control and Preventions Division of Laboratory Sciences

For TSNAs only, this was carried out with an increased number of pouches (N=15 in all cases)

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It is also essential for the material to be eco-friendly to be easily recycled, causing no harm to the environment