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Research has shown that a combination of medication and behavioural counselling improves the likelihood of quitting smoking

An attractive effect may be obtained in a number of ways, such as changing the appearance of the product and the smoke, decreasing the harshness of the smoke, and inducing a pleasant experience of smoking

There have been reports of depression, mania, psychosis, hallucinations, paranoia, delusions, homicidal ideation, aggression, hostility, anxiety, and panic, as well as suicidal ideation, suicide attempt, and completed suicide in patients attempting to quit smoking while taking CHANTIX [see Warnings and Precautions (5.1)]

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Some studies report slightly higher T levels in smokers but these results are inconsistent, likely influenced by other factors