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Mechanistically, p53 decreases the monoubiquitination rate of histone H2B on lysine 120 (H2Bub1) in the SLC7A11 gene regulatory region by facilitating the nuclear translocation of the deubiquitinase USP7, leading to the inactivation of SLC7A11 expression in erastin-treated cells [122]

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These would be considered approved B12 forms for thyroid patients: Methylcobalamin Hydroxycobalamin (5) Adenosylcobalamin (6) What types of B12 should you avoid