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Bentham Science Publishers, pp 276292 Ramzy D et al (2006) Elevated endothelin-1 levels impair nitric oxide homeostasis through a PKC-dependent pathway

Dry tobacco leaves with hand made cigarette over white background Captions are provided by our contributors

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The instrument is intended to gather meaningful insight on five areas relevant to TNP use: Perceived health risks (long and short term) Perceived addiction risks Perceived harm to others Practical risk Social risk The instrument has been developed and validated using concept elicitation and cognitive debriefing interviews with TNP users and modern psychometric techniques in cross-cultural studies