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Sperm health is a key factor in successful reproduction, yet millions of men unknowingly compromise their fertility through smoking

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Medication-assisted treatment within a comprehensive clinical program addresses the neurological and psychiatric dimensions of withdrawal even without a stimulant-specific approved medication

Sample Size and Power Calculations As no data are available in the literature on the efficacy of varenicline for gradual cessation in patients with COPD who are poorly motivated to quit, our sample size calculation was based on the cessation rates observed for abrupt cessation in patients with COPD motivated to quit smoking receiving a combination of varenicline and smoking cessation counseling

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