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Introduction Lower urinary tract symptoms (LUTS) are highly prevalent worldwide, affecting up to 70% of adult men and women, depending on the study population, age, and methodology ( There is a variation in the definition of chronic diseases regarding the included diseases and their duration ( Oxidative stress is an overload of oxidants and free radicals, mainly reactive oxygen species (ROS) such as superoxide radical anion (O 2 ), hydrogen peroxide (H 2 O 2 ), hydroxyl radical (HO ), and reactive nitrogen species (RNS) including nitric oxide (NO) and peroxynitrite (ONOO ), due to increased production and/or compromised antioxidant defenses

The enzymatic cycle of TGR (Fig

Alpha-lipoic acid (ALA): Works with glutathione to combat oxidative stress and support mitochondrial health

It does not automatically represent the ideal target for every person

Protective autophagy antagonizes oxaliplatin-induced apoptosis in gastric cancer cells