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Sun protection: Use daily sun protection (SPF, shade, protective clothing) when targeting skin-regeneration outcomes to reduce UV-driven breakdown of collagen and elastin

Frequency of administration All clinical trial cohorts used once-weekly subcutaneous injection

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Its a series of simple, deliberate actions that, when combined, create a powerful defense against contamination

That is precisely why the documented starting dose is a conservative 2 mg once weekly and why the escalation is unhurried the ladder is calibrated to the combined receptor load, not to any one arm