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Lyrically, despite four songwriters, the consistent direction is dark, with middle-of-the-night tales that often drill into strained relationships

Reynolds Tobacco Company's advertising agency also created ads and election guides where the mascot acted as a mediator between feuding political parties, in effect portraying Kool cigarettes as a remedy for heated political debates

NRF2-dependent survival in T-B2B cells is mediated by uncoupling stress from the AKTGSK3 axis Our previous data indicated that chronically smoke-exposed cells acquire stress-resistant phenotypes characterized by the constitutive activation of NRF2

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