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Collectively, these data suggested the limited activity of CB-839 monotherapy in CLL cell lines

Age-Related Muscle Loss Age-related muscle loss, or sarcopenia, is common and relatively preventable with sound nutritional practices and regular physical activity

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In OA, chronic low-grade inflammation can lead to further degeneration of joint cartilage, sclerosis of subchondral bone, and the formation of osteophytes, thereby aggravating joint damage and pain [14]