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Acceptable model fit was obtained for this model [ 2 (1) = 5.1, p = .02

Factual Insight #2: Research published in Nicotine & Tobacco Research (Oxford Academic, 2021) found that nicotine absorption from oral pouches follows a dose-dependent pattern higher-mg pouches produce measurably higher peak plasma nicotine concentrations, with absorption largely complete within 2030 minutes of placement

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The Dominican regions of Martn Garcia, Villa Gonzlez, Mao, Piloto, Navarrete, and Yamas each contribute leaves with their own identity, shaped by local soil and climate conditions

These findings emphasize the need to evaluate both ingestion and inhalation exposure routes, with inhalation presenting a potentially higher carcinogenic threat