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For optimal results, use consistently with a balanced diet and exercise

But the same 2025 review that catalogs those effects also underscores that only three human clinical trials have been published and that the compound remains investigational, with regulators having flagged it precisely because human safety and efficacy are not established

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Increased blood flow means that more oxygen can be transported to the muscles, fatigue onset is delayed, and overall endurance increases

[DOI] [PubMed] [Google Scholar] 168.Andersen J.V., Jakobsen E., Westi E.W., Lie M.E.K., Voss C.M., Aldana B.I., Schousboe A., Wellendorph P., Bak L.K., Pinborg L.H., et al