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Long term effects of Opioid addiction can result in loss of white matter in the brain, which affects decision making and behavior control

CONCLUSION The ever-growing tobacco product landscape complicates tobacco control, especially as stakeholders, including regulatory authorities, independent scientists, and the tobacco industry, tend to compare the toxicity and health effects of new tobacco products to cigarettes, focusing on the relative rather than the absolute risk of these new products

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The BPRF suggests that average smoking exposure raises the risk of COPD by an average of 72%, yielding an ROS of 0.54