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A has a major role in stimulating glutamate release by microglial cells and preventing neurons from accumulating excess glutamate, which means that A basically blocks glutamate uptake

IMPDH2 promotes colorectal cancer progression through activation of the PI3K/AKT/mTOR and PI3K/AKT/FOXO1 signaling pathways

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Subjective improvement without objective measurement is insufficient for evaluating response