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First of all, intracellular iron generally exists in the form of Fe 2+ , which can produce OH through the Fenton reaction, and then react with polyunsaturated fatty acids in the plasma membrane to produce ROS, resulting in iron-regulated death
Ghati et al., 2021
A form of iron called iron protein succinylate has been demonstrated to havepotential tolerability and efficacy advantages over other forms of supplemental iron in the treatment of iron-deficiency anemia (Cremonesi 1993