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The cost of the packaging for the Humiflex pack worked out at nearly 82c per 1,000 cigarettes, as opposed to 40c for the Marlboro flip-top box and 32c for the soft pack

Researchers and doctors, however, dispute these claims, citing lung injuries and deaths among vape users as evidence that vaping poses serious health risks

The mitochondrial Rho GTPase (Miro) family has a central role in regulatory mechanisms

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PMI has always tried to rehabilitate its image, but its move into cigarette alternatives gave it a more persuasive message, said Deborah Arnott, chief executive of the campaigning public health charity Action on Smoking and Health