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Remodeling in AF of sarcoplasmic reticulum calcium ATPase underlies sequestration of intracellular calcium between beats, and/or altered regulation of sarcoplasmic reticulum calcium ATPase by phospholamban and sarcolipin

Treatment may include: medical detox residential treatment intensive outpatient programs trauma-informed therapy medication-assisted treatment when appropriate Recovery focuses on addressing the root causes of substance use and helping individuals build stable, healthy lives beyond addiction

[173] Human Rights Watch interview with Ricardo M., 14, Shelby County, Kentucky, August 7, 2013

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