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A4: Yes

doi: 10.1007/s00580-014-2040-5

Linear growth, expressed as centimetres and height for age z-score (HAZ), and weight expressed as kilograms, weight for age (WAZ) and weight for height (WHZ) will be compared between the study groups

-Catenin binds to the Col1a1 promoter region, and this combination is related to the activity of Wnt/-catenin signalling, indicating that the canonical Wnt signalling pathway is involved in the bone phenotype of DHCR7 and INSIG1/2 defects