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Looking deeper into the data, 60% of participants on CagriSema achieved at least 20% weight loss

While multiple compounds and approaches have been suggested in the preclinical setting as potential treatments for SCA3 [174, 178], little has translated to clinical studies, which is clear by the small number of interventional trials carried out so far

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In the MSG group, an increment in local inflammation, edema, interstitial hemorrhage, and Hyaline casts were observed multi-focally from the cortex to inner medulla along nephrons