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Many cytokines use the Janus kinase (JAK) and signal transducer and activator of transcription (STAT) pathway to exert their effect in the pathology of RA, rendering them amenable to therapeutic blockade with Jakinibs which have proven effective for the treatment of RA

Figure 4 7.2 Psoriasis Psoriasis is a chronic, non-infectious, systemic inflammatory disease of autoimmune origin