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These varying regulatory landscapes have significantly influenced market development and product innovation in different regions
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Mice genetically deficient in miR - 223 displayed markedly exacerbated experimentally induced colitis, hyperactivated NLRP3 , and IL - 1 release, while mice with overexpressed miR-223 displayed the opposite effects [185], suggesting that miR - 223 represents a novel target for reducing the inflammatory response
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