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Given that several client proteins display acidic residues at the C-terminal position, our data are suggestive of a broad modulatory function of this residue in secretory trafficking

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In a situation where a chronic disease is responsible for anemia, it may be covered up by the disease, and hence, anemia may be identified through tests for another ailment

In the PCOS ovarian microenvironment, key functional cells such as granulosa cells are particularly vulnerable to this pathway, which directly impairs follicular development and maturation

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