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They demonstrate slower dissociation rates (over 30 minutes) while avoiding covalent and permanent bonds that are often linked to higher dissociation constant (Kd) values (132, 133)

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As the body cannot naturally produce Vitamin B12, it must be obtained through diet or supplementation

Metformin (for diabetes), proton pump inhibitors (such as omeprazole or esomeprazole), and H2 blockers (such as famotidine) can all reduce B12 absorption over time

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