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doi: 10.1016/j.febslet.2005.06.046 51 DixitR.WasiullahX.MalaviyaD.PandiyanK.SinghU

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The smooth endoplasmic reticulum contains microsomes that are involved in bilirubin conjugation, detoxification (cytochrome P450dependent isoenzymes), steroid synthesis, cholesterol synthesis, and bile acid synthesis

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Algunos autores han sealado que la paroniquia asociada al tratamiento con inhibidores del EGFR es secundaria a la fragilidad cutnea en relacin con el adelgazamiento del estrato crneo y la reduccin en la tasa de proliferacin de los queratinocitos69