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Critically, both subjects and investigators were blinded to the group assignment, ensuring impartiality throughout the study

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Moreover, the immunomodulating effect of the combination of selenomethionine and myoinositol in HT was confirmed by the fact that after treatment the level of the chemokine CXCL10, which is a potent chemoattractant for activated T-lymphocytes, also decreased, suggesting the possibility of reducing the risk of progression of euthyroidism to hypothyroidism (81)

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