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Researchers believe GLP-1 medications may influence nicotine dependence because the systems that regulate appetite and addiction share overlapping reward pathways, including dopamine signaling, impulse control and reward reinforcement

The modifying variable of pack-years smoked (years-quit) must be transformed through exponentiation for a more intuitive interpretation of results since it is modeled as a loglinear term

As part of its efforts to reduce tobacco-related harm, the FDA announced that it was exploring a product standard to lower nicotine in cigarettes to minimally addictive or non-addictive levels