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The natural flavonoid fisetin induces apoptosis in HCT-116 colon cancer cells by inhibiting HSF1 binding to the HSP70 and BAG3 promoters, thereby suppressing the heat shock response and promoting cell death

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To assess the overall status of the transsulphuration pathway, we also measured related metabolites involved in the pathway, namely, methionine (Met), S-adenosyl methionine (SAM), S-adenosyl homocysteine (SAH) and cysteine (Cys) in nRBC, iRBC, nMed and iMed (Fig

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