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Although STTPs do not necessarily include formal reporting requirements back to the SBIR office, AF claims that of the 108 STTP/SMTPs signed to date, 10 are inactive while 45 have generated outcomes that are now in the hands of the customer. 41 The AF target is to reach STTP agreements for 20 percent of prior-year Phase II awards, although this will clearly be challenging, as Figure 4-4 indicates

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The gene encoding USP25 also resides on human chromosome 21 (Valero et al., 1999), USP25 is involved in protein degradation by the 26S proteasome (Valero et al., 1999)