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doi: 10.1189/jlb.5A0116-022R Summary Keywords serine protease inhibitor superfamily (SERPIN), anti-inflammation, autoimmune disease, infectious disease, Severe Acute Respiratory Syndrome Coronavirus2 (SARS-CoV-2) Citation Mazzuca C, Vitiello L, Travaglini S, Maurizi F, Finamore P, Santangelo S, Rigon A, Vadacca M, Angeletti S and Scarlata S (2024) Immunological and homeostatic pathways of alpha -1 antitrypsin: a new therapeutic potential