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Coupled with the multiple endpoints of interest and myriad exposures (note that this does not just mean the list of product categories, though that is long enough, but also specifics of the products, dosage, and other variables), a literature an order of magnitude larger than what exists, and with average quality of at least that of the 75th percentile of quality for this literature, would only begin to be informative

The decline is not a result of a single dramatic policy shift