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Studies have shown that in sperm from diabetic patients, increased acetylation levels of H3K9 and H3K14 lead to abnormal open chromatin structures associated with gene promoter regions, ultimately interfering with the expression of genes required for spermatogenesis [194, 195]

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Glioblastoma (GBM), classified as a WHO IV glioma, is marked by its dismal prognosis, extensive tumor heterogeneity, and the absence of effective treatments, boasting a mere 5-year survival rate of 7.2% [1, 2]

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According to the statistics, more than 60 million Americans take APAP every week