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IV or injectable glutathione is a different story: India's drug regulator (CDSCO) clarified in May 2026 that cosmetic products, including glutathione drips, cannot legally be administered by injection for skin-lightening purposes

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Monitoring of electrolytes, including sodium, potassium, bicarbonate, magnesium, and phosphorus, is important, and the presence of acidosis is a risk factor for poor outcome in acute liver failure and has been incorporated into some prognostic models