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My feeling is that if you use any smaller gauge of needle you risk damaging the surrounding tissue at the injection site

Safety Toxicity No toxic or adverse effects have been associated with large intakes of vitamin B 12 from food or supplements in healthy people

For weight-loss evidence context, review Mayo Clinic information on B12 injections and weight loss

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After testing to determine whether an HCG injections therapy program is right for you, you may then choose to follow an HCG diet