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Smokers face is described as: Lines or wrinkles on the face, typically radiating at right angles from the upper and lower lips or corners of the eyes, deep lines on the cheeks, or numerous shallow lines on the cheeks and lower jaw. ( Figure 236-2 .) A subtle gauntness of the facial features with prominence of the underlying bony contours.6 The oral cavity of smokers often shows signs of prolonged exposure to tobacco in the form: Yellow and brown teeth ( Figures 236-3, 236-4, and 236-5 )

There have also been strain-dependent findings in mice, which are consistent with a genetic susceptibility to e-cigarette effects

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But notably, in terms of public health implications for those who can make the complete switch to e-cigarettes, we do believe that there is some harm reduction potential