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Published, JBC Papers in Press, November 22, 2004

Although results vary substantially between individuals, many before-and-after comparisons start showing noticeable improvements around the second month

After chronic (18 mo) administration of the pineal gland preparation epithalamin the amount of stromal cells-precursors, CD4+ and Mac-1(+)-cells in old bone marrow increased, improved the migration of T-cell precursors from bone marrow to thymus and their proliferative potential

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