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"We believe that 60 to 70 percent of our success is due to the way tobacco is dried and the time spent on fermentation and aging -- we don't rush things," says Castillo

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Nature 346:561564 Mazzone P, Tierney W, Hossain M, Puvenna V, Janigro D, Cucullo L (2010) Pathophysiological impact of cigarette smoke exposure on the cerebrovascular system with a focus on the blood-brain barrier: expanding the awareness of smoking toxicity in an underappreciated area