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However, in terms of cytokines and chemokines, such as GM-CSF, IFNg, IL-2, IL-4, IL-13, GRO, sCD40L and MCP-3, data from sputum samples suggests that e-cigarette use leads to an overall reduction in their concentrations in the lower airways (134)

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That is because the lungs not only absorb nicotine faster than the upper sections of the respiratory system, but they also offer a gateway that carcinogens can easily exploit

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[accessed 27 January 2023.] [13] Is Vaping Any Healthier Than Smoking?, Kirstie Ganobsik, HealthDay