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Ellis, J

And one can't simply take the tobacco companies' announcements at face value

Critically, our findings are not meant to detract from the substantive cancer risks associated with smoking which remains the single largest preventable cause of cancer worldwide [54], and for which even very low levels of exposure are associated with an increased risk of cancer [46]

However, their excessive presence can lead to increased irritation, pronounced bitterness, and a negative impact on the overall sensory experience [9]

These risk patterns were consistent between sexes and across histological types, and were not explained by the type of cigarettes smoked, levels of inhalation or cholesterol and beta-carotene intake