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Heavy drinkers' nicotine metabolite ratio - a biomarker that indicates how quickly a person's body metabolizes nicotine - reduced as they cut back on their drinking

It has long been known that in mice, inflammasome activation and IL-1 accelerate tumor invasiveness, growth, and metastatic spread [65]

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The nAChRs regulated B lymphocyte activation and immune response through CD40 signaling pathway [145, 146]

Bacterial infection is a common trigger of acute exacerbations in COPD patients, accelerating lung function decline, worsening quality of life and increasing mortality 33