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Nicotine replacement therapy is 98% safer than smoking

Soporowski likes to try and intimidate females with personal attacks but that will never work on me

That's a huge piece of information that explains a lot about the Smoking Man's actions over the years he's often seemed to toy with Mulder, and even when he and Agent Dana Scully (Gillian Anderson) seemed close to discovering the truth of the Smoking Man's plans, Bush seemed unwilling to kill Mulder to stop him

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So, with varenicline withdrawn and a similarly effective treatment available, we should have seen lives saved as people who would have taken varenicline were encouraged to try cytisine instead