In fact, one patient had a positive direct antiglobulin test (albeit weak reactivity) and an increased reticulocyte count (but not nearly enough to explain the severe macrocytosis)
This article examines what each compound is, how they work, the current evidence base, and the significant regulatory and safety considerations UK patients and clinicians need to understand
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While megadoses of up to 2,000 mcg are considered safe in treating B12 deficiency, its always best to avoid excessive amounts of any vitamin, especially when its not needed
A deficiency in B12 can lead to nerve damage, causing symptoms like tingling or numbness in the hands and feet