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Description

Spinal cord segments L4L6 were removed, post-fixed in the same solution, cryoprotected in 10% and 20% sucrose for 23 days and frozen in liquid isopentane

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Evidence suggests that calcium accumulation in the mitochondria, accompanied by high oxidative stress, affects its permeability and depletes ATP reserves leading to the necrotic death of the cell or to the release of cytocrome C and apoptosis [14]

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