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The subsequent ASPEN Phase III trial confirmed these findings, with brensocatib reducing annualized exacerbation rates by 21% (10 mg) and 19% (25 mg) compared to placebo (adjusted p = 0.004 and p = 0.005, respectively)

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137 Vitamin E Vitamin E, a family of compounds that includes tocopherols and tocotrienols, has the ability to end free radical chain reactions, in which one free radical leads to generation of another, and protects lipids, including those in cell membranes, from oxidative damage

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