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The new insight into the inflammatory response following focused ultrasound-mediated bloodbrain barrier disruption

The review also documented how GCL expression is transcriptionally upregulated by electrophiles through antioxidant response elements (ARE/EpRE) in the GCLC and GCLM promoters establishing the Nrf2/ARE pathway as the master regulator of GSH biosynthetic capacity under stress conditions

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10.1016/j.nbd.2013.08.007 Neurobiol