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One study showed that AMs from bronchoalveolar lavage fluid (BALF) of smokers and e-cigarette users are phenotypically distinct, with macrophages from e-cigarette vapers having elevated inducible nitric oxide synthase (marker for M1 macrophages) expression and reduced CD301a (marker for M2 macrophages) expression compared with nonsmokers or smokers(29)

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Since there is more moisture content within the resins in herbs compared to cured tobacco, they may not burn efficiently, thereby resulting in higher tar/smoke ratios in experiment results obtained through the use of ASMs

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Ryan Isaac: Majority