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Nevertheless, these results provide strong clinical evidence indicating that children with ASD were accompanied by oxidative stress marker aberrations, and the dysregulated oxidative stress marker profile in ASD children may offer novel insight into molecular pathways that confer vulnerability to the disease onset and/or progression

[5] Toxicity, safety, and potential side effects [edit] General observations [edit] There is limited safety information available on the effects of kava consumption, but in general, moderate consumption appears unlikely to be harmful, while there is evidence of harm from heavy use

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In both cases, however, it is not clear whether the non-responsiveness was due to resistance or due to other operational factors

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